# Against the Gradient

Summer DB entity ID: d905d0a1\-4fc6\-469f\-ae2a\-13b56db7b174

Steam App ID: 664660

A microscopic world is in need of your help\! Add transporters to membranes to move molecules and ions into and out of cells\. Your goal is to reach specific concentrations\.   Over 20 unique puzzles will help you master the principles of cellular transport\. Use channels, co\-transporters, and antiporters to master facilitated diffusion and active transport\.   Think you understand how transporters diffuse molecules and ions across the membrane? Try making your own puzzles with the built in level editor\!    Features:    Over 20 puzzles ranging from a gentle introduction to challenging mind benders\.   Speed up and slow down time to play at your own pace\.   16 transporters including real proteins found in your body and imaginative nano\-robots\.   Puzzle mechanics based on real biological principles of cellular transport\.   Built\-in level editor lets you take control and make your own levels to challenge your friends\!

## Game information

- Type: game

- Developer: Cogent Education

- Publisher: Cogent Education

- Release date: Jul 10, 2017

- Coming soon: false

- Free to play: false

- Parent Steam app: Not collected

- Genres: Casual, Indie, Simulation

- Categories: Single\-player, Steam Achievements, Steam Cloud, Includes level editor, Family Sharing

- Platforms: windows, mac, linux

- Website: Not collected

- Screenshots: https://shared\.akamai\.steamstatic\.com/store\_item\_assets/steam/apps/664660/ss\_d3ec2291f674543e16ed63617bbea4bf63a73295\.1920x1080\.jpg?t=1499689269, https://shared\.akamai\.steamstatic\.com/store\_item\_assets/steam/apps/664660/ss\_40ac6f619437718f25b8d9c2898900fd9086d72c\.1920x1080\.jpg?t=1499689269, https://shared\.akamai\.steamstatic\.com/store\_item\_assets/steam/apps/664660/ss\_d594115db34d03a7acb4077f0734260da0b0b281\.1920x1080\.jpg?t=1499689269, https://shared\.akamai\.steamstatic\.com/store\_item\_assets/steam/apps/664660/ss\_133c463b35c77a697cecac4ba11eec2e483ac229\.1920x1080\.jpg?t=1499689269, https://shared\.akamai\.steamstatic\.com/store\_item\_assets/steam/apps/664660/ss\_6fa84f649b1f5daf40f4bbb4c8a0a4f40984887e\.1920x1080\.jpg?t=1499689269

- Price: 299 minor units USD; discount 0%

- Price country: US

## Observed metrics

- Current players: 0

- Steam review count: 3

- Steam positive reviews: 3

- Steam negative reviews: 0

- Steam positive percentage: 100%

- Summer DB rating: No native votes

Review filters: \{"language":"all","review\_type":"all","purchase\_type":"all","filter\_offtopic\_activity":0\}

## Player history

[Seven-day chart data as Markdown](/api/v1/entities/d905d0a1-4fc6-469f-ae2a-13b56db7b174/player-metrics?days=7&format=markdown) · [JSON](/api/v1/entities/d905d0a1-4fc6-469f-ae2a-13b56db7b174/player-metrics?days=7)

Chart values are hourly observed maxima. The sampled 24-hour peak and missing intervals carry explicit coverage; history before collection is unknown.

## Sources and freshness

- Catalog membership: store\_catalog

- Catalog observed: 2026\-09\-28T16:58:32\.455488\+00:00

- Details observed: 2026\-09\-23T00:13:18\.278118\+00:00

- Player count observed: 2026\-09\-23T00:13:21\.548896\+00:00

- Reviews observed: 2026\-09\-23T00:13:19\.297939\+00:00

Full provenance: \{"urls":\{"price":"https://store\.steampowered\.com/app/664660/","catalog":"https://api\.steampowered\.com/IStoreService/GetAppList/v1/","details":"https://store\.steampowered\.com/app/664660/","players":"https://api\.steampowered\.com/ISteamUserStats/GetNumberOfCurrentPlayers/v1/?appid=664660","reviews":"https://store\.steampowered\.com/appreviews/664660"\},"price":"2026\-09\-23T00:13:18\.278118\+00:00","source":"steam","catalog":"2026\-09\-28T16:58:32\.455488\+00:00","country":"US","details":"2026\-09\-23T00:13:18\.278118\+00:00","players":"2026\-09\-23T00:13:21\.548896\+00:00","reviews":"2026\-09\-23T00:13:19\.297939\+00:00","language":"en","editorial":null,"membership":"store\_catalog","observations":\{"price":"a88d9593\-db6b\-4ca3\-9b3f\-c0dd187c7c81","catalog":"b2974920\-d264\-4736\-baa7\-176590467fc1","details":"5c701a4d\-f514\-4a25\-8545\-6ffae7e8f3e1","players":"7328e613\-ba9c\-4046\-aebc\-8915b8379666","reviews":"6cf9ebb9\-01a5\-4abd\-8204\-f8b16274826b"\},"reviewFilters":\{"language":"all","review\_type":"all","purchase\_type":"all","filter\_offtopic\_activity":0\}\}

Native rating methodology: \{"count":0,"average":null,"entityId":"d905d0a1\-4fc6\-469f\-ae2a\-13b56db7b174","revision":0,"observedAt":null,"methodology":"arithmetic\-v1","distribution":\[0,0,0,0,0,0,0,0,0,0\]\}

Steam reviews are not Summer DB votes. Missing data is not zero. Player counts are observations, not historical peaks. A supplemental record does not establish that a game was delisted.

[Steam store](https://store.steampowered.com/app/664660/) · [JSON](/api/v1/games/d905d0a1-4fc6-469f-ae2a-13b56db7b174)